
1. Introduction: The Evolution of Acid Suppression Therapy For decades, Proton Pump Inhibitors (PPIs) have represented the standard of care for acid-related gastrointestinal disorders. However, real-world clinical data highlights persistent therapeutic gaps: Persistent Symptoms: In survey data of patients on daily PPI regimens, approximately 54% reported persistent reflux symptoms. High Recurrence: Up to 80% of...




